Neurobiology of Disease Sodium Channel Cleavage Is Associated with Aberrant Neuronal Activity and Cognitive Deficits in a Mouse Model of Alzheimer’s Disease
نویسندگان
چکیده
Brian F. Corbett,1,2 Steven C. Leiser,3 Huai-Ping Ling,3 Reka Nagy,3 Nathalie Breysse,3 Xiaohong Zhang,1,2 Anupam Hazra,1,2 Jon T. Brown,4 Andrew D. Randall,4 Andrew Wood,3 Menelas N. Pangalos,3 Peter H. Reinhart,3 and Jeannie Chin1,2,3 1Department of Neuroscience and 2Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, 3Discovery Neuroscience, Wyeth Research, Princeton, New Jersey 08543, and 4University of Bristol School of Physiology and Pharmacology, Bristol, United Kingdom
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